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Out of 61 rats (M. decumanus) caught in this locality and kept isolated in the institute
— most of them until death, 40 rats presented the nematode in the epithelium of the cardiac
portion of the stomach. Pathological changes were found in 18 among these 40 rats, in 9 cases
as marked papillomatous tumours of the same type as described above, while in the rest of
the cases the process must be considered a prehminary stage of true new growth. It was
further determined that the nematode could not only be found in the cardiac portion of the
stomach but also in the epithelium of the oesophagus, occasionally also in the epithehum of ’
the tongue and in the mucous membrane of the mouth.
Observations made on rats fed on cockroaches (P. americana) caught in the refinery,
gave the foUowing result:
For these experiments 4 wild brown rats from the neighbourhood of Copenhagen and 53 black
and white rats born and bred at the new anatomical-pathological Institute of the University
were used. The modern, and hitherto unused stables here did not at all harbour cock-
roaches. The rats were fed on cockroaches for one or 2 periods, every period being of 3 — 70
days duration. The number of cockroaches used as feeding-material varied, 2 rats were given
c. 100, the rest less. The rats with a few exceptions were not killed unless getting into agony.
On the whole, the experiments gave the fol lo wing results: In 3 rats the stomach presented
no pathological changes and especially no nematodes. On the other hånd parasites were found in
different numbers in the remaining 54 rats, 37 of which presented pathological changes simul-
taneously. In 11 cases the process appeared to be but slightly marked, in 27 cases a .higher
stage of development was reached, which in 7 cases consisted in enormous tumour-growths of
the described type.
The nematode and eggs found in these rats corresponded to those observed in the rats from
Dorpat and in the rats caught in the sugar refinery. Most unfortunately — however — the
sugar refinery was destroyed by fire in February 1912, and experiments consequently could not
be carried on, as at this point of time no other locality in Copenhagen or elsewhere seemed to
harbour the P. americana.
The results of all series of experiments are seen from the table:
Sort of rats
Number of
rats
examined
The worm
found in
The worm found ; True
coincident with newgrowth
path. changes in i found in
Wild rats:
m. decumanus
m. rattus
m. alexandrinus
Black and white laboratory rats
Total...
m. decumanus from sugar refinery
Black and white laboratory rats fed on P.
americana from sugar refinery
Total...
844
21
2
i 277 j
(»
;
I 1I41 [
1 « i
67
40
54
18
37
1
9
7
118
94
55
16
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