Full resolution (JPEG) - On this page / på denna sida - VI. Chyle, Lymph, Transudates and Exudates - I. Chyle and Lymph
<< prev. page << föreg. sida << >> nästa sida >> next page >>
Below is the raw OCR text
from the above scanned image.
Do you see an error? Proofread the page now!
Här nedan syns maskintolkade texten från faksimilbilden ovan.
Ser du något fel? Korrekturläs sidan nu!
This page has never been proofread. / Denna sida har aldrig korrekturlästs.
CHYLE AND LYMPH. 351
and the lymph is therefore a measure of the work in these. The close
relation between lymph formation and the work of organs has also been
showr
n for several of them, especially for the liver. Starling has
shown that after the introduction of lymphagogues of the first series,
chiefly liver lymph is secreted, which he claims is a proof against Heiden-
hain’s view, and he explains the increased permeability of the vessel
wall by the fact that these bodies have an irritating, poisonous action.
On the contrary, Ashek explains this increased lymph flow by the state-
ment that the substance in question—as well as those influences which
incite the activity of the liver—produces an increased formation of lymph
in these organs. This view is supported by experiments upon the action
of lymphagogues on blood coagulation and liver activity (Delezenne
and others), for, according to Gley, these bodies have at the same time
a lymphagogue action and an action upon the secretion of the glands.
We have no direct evidence of the action of the lymphagogues of the
first series upon the organs, but we know from Kusmine’s work that
peptone, leech extract, and the extractives of the crab-muscles act directly
upon the liver-cells and bring about morphological changes. The con-
nection betwr
een organ activity and lymph formation has also been
shown upon muscles and glands by others besides the above-mentioned
investigators (Hamburger, Bainbridge 1
).
The extent of organ work essentially influences the quantity and
properties of the lymph. Still from this we cannot draw any posi-
tive conclusions as to whether the lymph formation is brought about
by physico-chemical processes alone or whether in this process a specific,
not closely definable secretory force is at work at the same time. In
regard to this much-disputed question, attention must be called in the
first place to the fact that the important works of Heidenhain, Ham-
burger, Lazarus-Barlow, and others, as well as the investigations of
Asher and Gies and of Mendel and Hooker 2
upon the lengthy post-
mortem lymph flow, have shown that the older filtration hypothesis is
untenable.
That osmotic processes play an important role in the lymph formation
is generally admitted and that the work of the glands and tissue cells
must cause a difference in the osmotic pressure on both sides of the capillary
wr
alls, has been shown by the researches of many investigators (Koranyi,
Starling, Roth, Asher and others). That this is so follows from
several circumstances, and especially from the fact that, in disassimila-
1
In regard to the works cited, as well as the literature upon lymph formation, see
Ellinger, "Die Bildung der Lymphe," Ergebnisse der Physiol., I, Abt. 1, 1902, and
Asher, Biochem. Centralbl., 4.
2
Amer. Journ. of Physiol., 7. See also footnote 1.
<< prev. page << föreg. sida << >> nästa sida >> next page >>
