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366 CHYLE, LYMPH, TRANSUDATES AND EXUDATES.
volatile fatty acids, such as formic acid, butyric acid and valeric acid.
There are also found urea, glucose (in diabetes), bile-pigments, and bile-
acids (in catarrhal icterus).
As more specific but not constant constituents of the pus must be
mentioned the following: pyin, which seems to be a nucleoprotein pre-
cipitable by acetic acid, and also pyinic acid and chlorrhodinic acid, which
have been so little studied that they cannot be more fully treated here.
In many cases a blue, more rarely a green, color, has been observed
in the pus. This depends on the presence of micro-organisms (Bacillus
pyocyaneus). From such pus Fordos and Lucke x
have isolated a crys-
talline blue pigment, pyocyanin, and a yellow pigment, pyoxanthose,
which is produced from the first by oxidation.
Appendix.
Lymphatic Glands, Spleen and Endocrinic Glands.
The Lymphatic Glands. The cells of the lymphatic glands are
found to contain the protein substances generally occurring in cells
(Chapter V). According to Bang 2
they also contain histone nucleates
(nucleohistone), but in smaller amounts and of a different variety from
the better-studied nucleohistone from the thymus gland. Proteoses
occur as products of autolysis. By a lengthy autolysis of lymph glands
Reh 3 found ammonia, tyrosine, leucine (somewhat scanty), thymine,
and uracil among the cleavage products. Besides the other ordinary
tissue constituents, such as collagen, reticulin, elastin, and nuclein, there
occur in the lymphatic glands also cholesterin, fat, glycogen, sarcolactic
acid, purine bases, and leucine. In the inguinal glands of an old woman
Oidtmann found 714.32 p. m. water, 284.5 p. m. organic and 1.16 p. m.
inorganic substances. In the cells of the mesenteric lymphatic glands
of oxen, Bang 4 found 804.1 p. m. water, 195.9 p. m. solids, 137.9 total
proteins, 6.9 p. m. histone nucleate, 10.6 p. m. nucleoprotein, 47.6 p. m.
bodies soluble in alcohol, and 10.5 p. m. mineral constituents.
The Thymus. The cells of this gland are very rich in nuclein bodies
and relatively poor in the ordinary proteins, but their nature has not been
closely studied. The chief interest is attached to the nuclein substances.
Kossel and Lilienfeld first prepared from the watery extract of the
gland, by precipitating with acetic acid and then further purifying, a
1
Fordos, Compt. Rend., 51 and 56; Lucke, Arch. f. klin. Chirurg., 3; Boland, Cen-
tralbl. f. Bakt. u. Parasit., I., 25.
2
Studio- over Nucleoproteider, Krietiania, 1902, and Hofmeister’e Beitrage, 4.
3 Hofmeister’a Beitrage, 3.
M. c.
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