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COLLOID. PSEUDOMUCIN. G25
Colloid. This name does not designate any particular chemical
substance, but is given to the contents of tumors with certain physical
properties similar to gelatin jelly. Colloid is found as a pathological
product in several organs.
Colloid is a gelatinous mass, insoluble in water and acetic acid; it is
dissolved by alkalies and gives a liquid which is not precipitated by
acetic acid or by acetic acid and potassium ferrocyanide. According to
Pfannenstiel ’ such a colloid is designated /3-pseudomucin. Some-
times a colloid is found which, when treated with a very dilute alkali,
gives a solution similar to a mucin solution. Colloid is very closely
related to mucin and is considered by certain investigators as a modified
mucin. An ovarial colloid analyzed by Panzer contained 931 p. m.
water, 57 p. m. organic substance, and 12 p. m. ash. The elementary
composition was C 47.27, H 5.8G, N 8.40, S 0.79, P 0.54, and ash 6.43
per cent. A colloid found by Wurtz 2
in the lungs contained C 48.09,
H 7.47, X 7.00, and 0(+S) 37.44 per cent. Colloids of different origin
seem to be of varying composition.
Mctolbumin. This name Scherer 3
gave to a protein substance
found by him in an ovarial fluid. The metalbumin was considered by
Scherer to be an albuminous body, but it belongs to the mucin group,
and it is for this reason called pseudomucin by Hammarsten.4
Pseudomucin. This body, wr
hich, like the mucins, gives a reducing
substance when boiled with acids, is a mucoid of the following com-
position: C 49.75, H 6.98, N 10.28, S 1.25, O 31.74 per cent (Hammar-
sten). With water pseudomucin gives a slimy, ropy solution, and it is
this substance which gives the fluid contents of the ovarial cysts their
typical ropy property. Its solutions do not coagulate on boiling, but
only become milky or opalescent. Unlike mucin, pseudomucin solutions
are not precipitated by acetic acid. With alcohol they give a coarse
flocculent or thready precipitate which is soluble even after having been
kept under water or alcohol, for a long time.
Paralbumin is another substance discovered by Scherer, which occurs
in ovarial liquids, and also in ascitic fluids, with the simultaneous presence
of ovarial cysts and rupture of the same. It is therefore only a mixture
of pseudomucin with variable amounts of protein, and the reactions of
paralbumin are correspondingly variable.
1
Arch. f. Gynak., 38.
2
Panzer, Zeitschr. f. physiol. Chem., 28; Wiirtz, see Lebert, Beitr. zur Kenntnis
des Gallertkrebses, Virchow’s Arch., 4.
3
Yerh. d. physik.-med. Gesellsch. in Wurzburg, 2, and Sitzungsber. der physik.-
rr.ed. Gesellsch. in Wurzburg fur 1864-1865; Wurzburg med. Zeitschr., 7, No. 6.
4
Zeitschr. f . physiol. Chem., 6.
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