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15
the saliva (RASMUSSEN 51). Fungi have also been isolated from the
nasal cavity. KüsTER (36) mentions that RENON obtained Aspergillus
fumigatus from nasal secretion. PAULSEN (49) found several cases
of the presence of species of Mucor and Aspergillus in the nose.
SCHUBERT (57) reports a case of stoppage of the nasal passages by
the vigorous growth of Aspergillus fumigatus, and HASSLAUER (25)
found three cases of the presence of »Schimmelpilze» in diseased
nose. Nasal catarrh has further been claimed by Srtorı (61) to
result from inhalation of spores of Penicillium crustaceum.
The ear is also subject to invasions of fungi, but they are in
most cases unable to penetrate the epidermis, and the healthy ear
is not endangered. SIEBENMANN (58) met among others, with
Aspergillus fumigatus, A. niger, A. flavus, A. nidulans, Mucor, and
species of Penicillium, and Supre (62) has recently recorded some
not further determined moulds, belonging to the genera Penicillium,
Mucor, and Aspergilius.
In rare cases the eye becomes diseased due to the attacks of
moulds, causing what physicians call keratomycosis. Aspergillus
fumigatus seems to be the species most commonly reported from
diseased eye Piaur (50), but A. nidulans, A. flavus, and species of
Rhizopus have also been met with (TRUBIN 66).
Bronchopneumonomycosis or the fungal disease of the lungs and
the bronchial tubes, due to the invasion of species of Mucor and
Aspergillus is, however, by far the most serious mycosis in man
and animals. RENon (52) found that a certain class of people in
Paris, employed to feed young pigeons with mouldy grain, taken
in the mouth, masticated, and put in the mouths of the birds,
suffered severely from pulmonary mycosis strikingly resembling
tuberculosis in appearance and effect. He states that Aspergillus
fumigatus may play a primary or secondary role in the development
of the disease in both man and animals, and considers this species
not merely a simple saprophyte but a true parasite. MOHLER and
BuckLEY (42) have an interesting discussion of pulmonary mycosis
in birds and conclude that the lungs, particularly of birds, are
veritable propagating houses for A. fumigatus. Numerous additional
cases of pneumonomycosis in both man and animals are given by
PrauTt (50). The experimental phase of the subject has been treated
by a number of investigators, which by injection of spores in-
traabdominally and intravenously in animals, have conclusively
proven the pathogenicity of different species of Mucor and Aspergillus.
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